Mesoporous Polydopamine Nanoparticles Attenuate Morphine Tolerance in Neuropathic Pain Rats by Inhibition of Oxidative Stress and Restoration of the Endogenous Antioxidant System

• Hauptverfasser: Yaswanth Kuthati (VerfasserIn), Prabhakar Busa (VerfasserIn), Srikrishna Tummala (VerfasserIn), Vaikar Navakanth Rao (VerfasserIn), Venkata Naga Goutham Davuluri (VerfasserIn), Yen-Peng Ho (VerfasserIn), Chih-Shung Wong (VerfasserIn)
• Format: Buch
• Veröffentlicht: MDPI AG, 2021-01-01T00:00:00Z.
• Schlagworte: article
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Oxidative stress resulting from reactive oxygen species (ROS) is known to play a key role in numerous neurological disorders, including neuropathic pain. Morphine is one of the commonly used opioids for pain management. However, long-term administration of morphine results in morphine antinociceptiv...