Nutritionally physiological cell culture medium and 3D culture influence breast tumour proteomics and anti-cancer drug effectiveness

Many drugs have been discontinued during phase II/III breast cancer clinical trials due to lack of clinical efficacy, indicating shortcomings in predictive value of preclinical data. Nutrient availability in the tumour cell microenvironment and the dimensionality of in vitro tumour cells likely impa...

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Main Authors: Xiaodan Zhang (Author), Tianhong Cheng (Author), Ellie Cho (Author), Wenjia Lu (Author), Delphine Denoyer (Author), Paul McMillan (Author), Kalyan Shobhana (Author), Swati Varshney (Author), Nicholas A. Williamson (Author), Alastair Stewart (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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