Discovery of novel conjugates of quinoline and thiazolidinone urea as potential anti-colorectal cancer agent

• Główni autorzy: Li Xiong (Autor), Huan He (Autor), Mengmeng Fan (Autor), Liping Hu (Autor), Fei Wang (Autor), Xiaomeng Song (Autor), Shengmin Shi (Autor), Baohui Qi (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Based on the obtained SARs, further structural optimisation of compound BC2021-104511-15i was conducted in this investigation, and totally ten novel quinoline derivates were designed, synthesised and optimised for biological activity. Among them, compound 10a displayed significant in vitro anticance...