Strategic use of levofolinic acid for methotrexate-induced side effects in juvenile idiopathic arthritis: a prospective observational study

• Autores principales: Giorgia Martini (Autor), Alessandra Meneghel (Autor), Michele Fastiggi (Autor), Filippo Dell'Apa (Autor), Fabio Vittadello (Autor), Francesco Zulian (Autor)
• Formato: Libro
• Publicado: BMC, 2023-02-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Objective To evaluate the efficacy of levofolinic acid (LVF) administered 48 h before methotrexate (MTX) in reducing gastrointestinal side effects without interference with drug efficacy. Methods A prospective observational study was performed including patients with Juvenile Idiopathic Art...