Maprotiline Suppresses Cholesterol Biosynthesis and Hepatocellular Carcinoma Progression Through Direct Targeting of CRABP1

Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related death and has a poor prognosis worldwide, thus, more effective drugs are urgently needed. In this article, a small molecule drug library composed of 1,056 approved medicines from the FDA was used to screen for antican...

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Main Authors: Cancan Zheng (Author), Yidong Zhu (Author), Qinwen Liu (Author), Tingting Luo (Author), Wenwen Xu (Author)
Format: Book
Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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