Maprotiline Suppresses Cholesterol Biosynthesis and Hepatocellular Carcinoma Progression Through Direct Targeting of CRABP1

• Main Authors: Cancan Zheng (Author), Yidong Zhu (Author), Qinwen Liu (Author), Tingting Luo (Author), Wenwen Xu (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related death and has a poor prognosis worldwide, thus, more effective drugs are urgently needed. In this article, a small molecule drug library composed of 1,056 approved medicines from the FDA was used to screen for antican...