Self-assembling protein nanocarrier for selective delivery of cytotoxic polypeptides to CXCR4+ head and neck squamous cell carcinoma tumors

• Автори: Elisa Rioja-Blanco (Автор), Irene Arroyo-Solera (Автор), Patricia Álamo (Автор), Isolda Casanova (Автор), Alberto Gallardo (Автор), Ugutz Unzueta (Автор), Naroa Serna (Автор), Laura Sánchez-García (Автор), Miquel Quer (Автор), Antonio Villaverde (Автор), Esther Vázquez (Автор), Ramon Mangues (Автор), Lorena Alba-Castellón (Автор), Xavier León (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2022-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Loco-regional recurrences and distant metastases represent the main cause of head and neck squamous cell carcinoma (HNSCC) mortality. The overexpression of chemokine receptor 4 (CXCR4) in HNSCC primary tumors associates with higher risk of developing loco-regional recurrences and distant metastases,...