Mechanisms of NAT10 as ac4C writer in diseases

• Main Authors: Lihua Xie (Author), Xiaolin Zhong (Author), Wenyu Cao (Author), Jianghua Liu (Author), Xuyu Zu (Author), Ling Chen (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the early stage, N4-acetylcytidine (ac4C) was regarded as a conservative nucleoside present on tRNA and rRNA. Recently, studies have shown that ac4C also exists in human and yeast mRNA. N-Acetyltransferase-like protein 10 (NAT10) is the first enzyme to be found to catalyze ac4C production in euka...