Mechanisms of NAT10 as ac4C writer in diseases

• Hauptverfasser: Lihua Xie (VerfasserIn), Xiaolin Zhong (VerfasserIn), Wenyu Cao (VerfasserIn), Jianghua Liu (VerfasserIn), Xuyu Zu (VerfasserIn), Ling Chen (VerfasserIn)
• Format: Buch
• Veröffentlicht: Elsevier, 2023-06-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

In the early stage, N4-acetylcytidine (ac4C) was regarded as a conservative nucleoside present on tRNA and rRNA. Recently, studies have shown that ac4C also exists in human and yeast mRNA. N-Acetyltransferase-like protein 10 (NAT10) is the first enzyme to be found to catalyze ac4C production in euka...