Heme Cytotoxicity And The Pathogenesis of Immune Mediated Inflammatory Diseases.

• Главные авторы: Rasmus eLarsen (Автор), Zélia eGouveia (Автор), Miguel P Soares (Автор), Raffaella eGozzelino (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2012-05-01T00:00:00Z.
• Предметы: article
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Heme, iron (Fe) protoporphyrin IX, functions as a prosthetic group in a range of hemoproteins essential to support life under aerobic conditions. The Fe contained within the prosthetic heme groups of these hemoproteins can catalyze the production of cytotoxic reactive oxygen species (ROS). Presumabl...