A Rapid and Sensitive UHPLC-MS/MS Method for Determination of Chlorogenic Acid and Its Application to Distribution and Neuroprotection in Rat Brain

• Main Authors: Chongfei Bai (Author), Xiaogang Zhou (Author), Lu Yu (Author), Anguo Wu (Author), Le Yang (Author), Jianping Chen (Author), Xue Tang (Author), Wenjun Zou (Author), Jianming Wu (Author), Linjie Zhu (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chlorogenic acid (5-CQA) is a phenolic natural product that has been reported to improve neurobehavioral disorders and brain injury. However, its pharmacokinetics and distribution in the rat brain remain unclear. In this study, we established a rapid and sensitive UHPLC-MS/MS method for the determin...