A Rapid and Sensitive UHPLC-MS/MS Method for Determination of Chlorogenic Acid and Its Application to Distribution and Neuroprotection in Rat Brain

• Hoofdauteurs: Chongfei Bai (Auteur), Xiaogang Zhou (Auteur), Lu Yu (Auteur), Anguo Wu (Auteur), Le Yang (Auteur), Jianping Chen (Auteur), Xue Tang (Auteur), Wenjun Zou (Auteur), Jianming Wu (Auteur), Linjie Zhu (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Chlorogenic acid (5-CQA) is a phenolic natural product that has been reported to improve neurobehavioral disorders and brain injury. However, its pharmacokinetics and distribution in the rat brain remain unclear. In this study, we established a rapid and sensitive UHPLC-MS/MS method for the determin...