Human F-ATP synthase as a drug target

• Egile Nagusiak: Christoph Gerle (Egilea), Chimari Jiko (Egilea), Atsuki Nakano (Egilea), Ken Yokoyama (Egilea), Chai C. Gopalasingam (Egilea), Hideki Shigematsu (Egilea), Kazuhiro Abe (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Practical and conceptual barriers have kept human F-ATP synthase out of reach as a target for the treatment of human diseases. Although this situation has persisted for decades, it may change in the near future. In this review the principal functionalities of human F-ATP synthase--proton motive forc...