Human F-ATP synthase as a drug target

• Main Authors: Christoph Gerle (Author), Chimari Jiko (Author), Atsuki Nakano (Author), Ken Yokoyama (Author), Chai C. Gopalasingam (Author), Hideki Shigematsu (Author), Kazuhiro Abe (Author)
• Format: Book
• Published: Elsevier, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Practical and conceptual barriers have kept human F-ATP synthase out of reach as a target for the treatment of human diseases. Although this situation has persisted for decades, it may change in the near future. In this review the principal functionalities of human F-ATP synthase--proton motive forc...