Human F-ATP synthase as a drug target

• Prif Awduron: Christoph Gerle (Awdur), Chimari Jiko (Awdur), Atsuki Nakano (Awdur), Ken Yokoyama (Awdur), Chai C. Gopalasingam (Awdur), Hideki Shigematsu (Awdur), Kazuhiro Abe (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2024-11-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Practical and conceptual barriers have kept human F-ATP synthase out of reach as a target for the treatment of human diseases. Although this situation has persisted for decades, it may change in the near future. In this review the principal functionalities of human F-ATP synthase--proton motive forc...