Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• Hoofdauteurs: Philippe-Henri Secretan (Auteur), Maxime Annereau (Auteur), Willy Kini-Matondo (Auteur), Bastien Prost (Auteur), Jade Prudhomme (Auteur), Lina Bournane (Auteur), Muriel Paul (Auteur), Najet Yagoubi (Auteur), Hassane Sadou-Yayé (Auteur), Bernard Do (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...