Treating Cancer by Targeting Telomeres and Telomerase

• Główni autorzy: Marko Ivancich (Autor), Zachary Schrank (Autor), Luke Wojdyla (Autor), Brandon Leviskas (Autor), Adijan Kuckovic (Autor), Ankita Sanjali (Autor), Neelu Puri (Autor)
• Format: Książka
• Wydane: MDPI AG, 2017-02-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Telomerase is expressed in more than 85% of cancer cells. Tumor cells with metastatic potential may have a high telomerase activity, allowing cells to escape from the inhibition of cell proliferation due to shortened telomeres. Human telomerase primarily consists of two main components: hTERT, a cat...