Treating Cancer by Targeting Telomeres and Telomerase
Telomerase is expressed in more than 85% of cancer cells. Tumor cells with metastatic potential may have a high telomerase activity, allowing cells to escape from the inhibition of cell proliferation due to shortened telomeres. Human telomerase primarily consists of two main components: hTERT, a cat...
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MDPI AG,
2017-02-01T00:00:00Z.
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