Nitric oxide synthase inhibition decreases tolerance to hyperoxia in newborn rats

• Auteurs principaux: M. R. Pierce (Auteur), C. A. Voelker (Auteur), I. R. S. Sosenko (Auteur), S. Bustamante (Auteur), S. M. Olister (Auteur), X.-J. Zhang (Auteur), D. A. Clark (Auteur), M. J. S. Miller (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 1995-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

We evaluated the effects of sustained perinatal inhibition of NO synthase (NOS) on hyperoxia induced lung injury in newborn rats. NG-nitro-Larginine-methyl-ester (L-NAME) or untreated water was administered to pregnant rats for the final 7 days of gestation and during lactation; followed by postnata...