Solubility Improvement of Benexate through Salt Formation Using Artificial Sweetener

• Hoofdauteurs: Okky Dwichandra Putra (Auteur), Daiki Umeda (Auteur), Eriko Fujita (Auteur), Tamami Haraguchi (Auteur), Takahiro Uchida (Auteur), Etsuo Yonemochi (Auteur), Hidehiro Uekusa (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2018-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Benexate, a drug used clinically as a defensive type anti-ulcer agent, has poor solubility and a bitter taste. To improve its solubility, a crystal engineering approach was proposed with the formation of novel salts using an artificial sweetener as a salt co-former. This was also expected to address...