Genetic dissection of anterior segment dysgenesis caused by a Col4a1 mutation in mouse

• मुख्य लेखकों: Mao Mao (लेखक), Márton Kiss (लेखक), Yvonne Ou (लेखक), Douglas B. Gould (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2017-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Ocular anterior segment dysgenesis (ASD) describes a spectrum of clinically and genetically heterogeneous congenital disorders affecting anterior structures that often lead to impaired vision. More importantly, 50-75% of patients with ASD develop early onset and aggressive glaucoma. Although several...