Genetic dissection of anterior segment dysgenesis caused by a Col4a1 mutation in mouse

• Auteurs principaux: Mao Mao (Auteur), Márton Kiss (Auteur), Yvonne Ou (Auteur), Douglas B. Gould (Auteur)
• Format: Livre
• Publié: The Company of Biologists, 2017-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Ocular anterior segment dysgenesis (ASD) describes a spectrum of clinically and genetically heterogeneous congenital disorders affecting anterior structures that often lead to impaired vision. More importantly, 50-75% of patients with ASD develop early onset and aggressive glaucoma. Although several...