TIGIT/CD226 Axis Regulates Anti-Tumor Immunity

• Principais autores: Jinah Yeo (Autor), Minkyung Ko (Autor), Dong-Hee Lee (Autor), Yoon Park (Autor), Hyung-seung Jin (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2021-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Tumors escape immune surveillance by inducing various immunosuppressive pathways, including the activation of inhibitory receptors on tumor-infiltrating T cells. While monoclonal antibodies (mAbs) blocking programmed cell death 1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic T lymphocyte-...