Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway

Tacrolimus-induced chronic nephrotoxicity (TIN) hinders its long-term use in patients. However, there are no drugs available in the clinic to relieve it at present. Astragaloside IV (AS-IV) is a saponin extract of the Astragalus which is widely used in the treatment of kidney disease. This study aim...

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Main Authors: Ping Gao (Author), Xiaoyi Du (Author), Lili Liu (Author), Hua Xu (Author), Maochang Liu (Author), Xinlei Guan (Author), Chengliang Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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