Antiepileptic Effects of Single and Repeated Oral Administrations of S-312-d, a Novel Calcium Channel Antagonist, on Tonic Convulsions in Spontaneously Epileptic Rats

We investigated the effects of single and repeated administrations of S-312-d (methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)-thieno-[2,3-b]pyridine-5-carboxylate), a newly synthesized L-type Ca2+-channel blocker, on tonic convulsions and absence-like seizures in the spontaneously epilepti...

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Main Authors: Taku Amano (Author), Zhu Aihua (Author), Hiroaki Matsubayashi (Author), Takahiro Seki (Author), Tadao Serikawa (Author), Masashi Sasa (Author), Norio Sakai (Author)
Format: Book
Published: Elsevier, 2004-01-01T00:00:00Z.
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Call Number: A1234.567
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