Antiepileptic Effects of Single and Repeated Oral Administrations of S-312-d, a Novel Calcium Channel Antagonist, on Tonic Convulsions in Spontaneously Epileptic Rats

• Váldodahkkit: Taku Amano (Dahkki), Zhu Aihua (Dahkki), Hiroaki Matsubayashi (Dahkki), Takahiro Seki (Dahkki), Tadao Serikawa (Dahkki), Masashi Sasa (Dahkki), Norio Sakai (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2004-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

We investigated the effects of single and repeated administrations of S-312-d (methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)-thieno-[2,3-b]pyridine-5-carboxylate), a newly synthesized L-type Ca2+-channel blocker, on tonic convulsions and absence-like seizures in the spontaneously epilepti...