A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation

• Váldodahkkit: Hao Chen (Dahkki), Yuanying Gong (Dahkki), Yufang Ma (Dahkki), Reid C. Thompson (Dahkki), Jialiang Wang (Dahkki), Zhixiang Cheng (Dahkki), Lixia Xue (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Glioblastoma multiforme (GBM) is a highly heterogeneous disease, which is initiated and sustained by various molecular alterations in an array of signal transduction pathways. Heat-shock protein 90 (Hsp90) is a molecular chaperone and is critically implicated in folding and activation of a diverse g...