A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation

• Asıl Yazarlar: Hao Chen (Yazar), Yuanying Gong (Yazar), Yufang Ma (Yazar), Reid C. Thompson (Yazar), Jialiang Wang (Yazar), Zhixiang Cheng (Yazar), Lixia Xue (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Glioblastoma multiforme (GBM) is a highly heterogeneous disease, which is initiated and sustained by various molecular alterations in an array of signal transduction pathways. Heat-shock protein 90 (Hsp90) is a molecular chaperone and is critically implicated in folding and activation of a diverse g...