Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury

• Main Authors: Qiaojing Yan (Author), Zhimin Mao (Author), Jingru Hong (Author), Kun Gao (Author), Manabu Niimi (Author), Takahiko Mitsui (Author), Jian Yao (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tanshinone IIA (Tan IIA), an active ingredient of Danshen, is a well-used drug to treat cardiovascular diseases. Currently, the mechanisms involved remain poorly understood. Given that many actions of Tan IIA could be similarly achieved by hydrogen sulfide (H₂S), we speculated...