Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury

• Egile Nagusiak: Qiaojing Yan (Egilea), Zhimin Mao (Egilea), Jingru Hong (Egilea), Kun Gao (Egilea), Manabu Niimi (Egilea), Takahiko Mitsui (Egilea), Jian Yao (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Tanshinone IIA (Tan IIA), an active ingredient of Danshen, is a well-used drug to treat cardiovascular diseases. Currently, the mechanisms involved remain poorly understood. Given that many actions of Tan IIA could be similarly achieved by hydrogen sulfide (H₂S), we speculated...