Neuroprotective Efficacy of a Nanomicellar Complex of Carnosine and Lipoic Acid in a Rat Model of Rotenone-Induced Parkinson's Disease

• Главные авторы: Olga Kulikova (Автор), Dmitry Troshev (Автор), Daniil Berezhnoy (Автор), Sergey Stvolinsky (Автор), Yulia Timoshina (Автор), Denis Abaimov (Автор), Olga Muzychuk (Автор), Alexander Latanov (Автор), Tatiana Fedorova (Автор)
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• Опубликовано: MDPI AG, 2023-06-01T00:00:00Z.
• Предметы: article
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Oxidative stress, accompanied by mitochondrial dysfunction, is a key mechanism involved in the pathogenesis of Parkinson's disease (PD). Both carnosine and lipoic acid are potent antioxidants, the applicability of which in therapy is hindered by their limited bioavailability. This study aimed t...