Neuroprotective Efficacy of a Nanomicellar Complex of Carnosine and Lipoic Acid in a Rat Model of Rotenone-Induced Parkinson's Disease

• Ngā kaituhi matua: Olga Kulikova (Author), Dmitry Troshev (Author), Daniil Berezhnoy (Author), Sergey Stvolinsky (Author), Yulia Timoshina (Author), Denis Abaimov (Author), Olga Muzychuk (Author), Alexander Latanov (Author), Tatiana Fedorova (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2023-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Oxidative stress, accompanied by mitochondrial dysfunction, is a key mechanism involved in the pathogenesis of Parkinson's disease (PD). Both carnosine and lipoic acid are potent antioxidants, the applicability of which in therapy is hindered by their limited bioavailability. This study aimed t...