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Clinical aspects of TP53 gene inactivation in diffuse large B-cell lymphoma

Abstract Background The knowledge about specific mechanisms generating TP53 dysfunction in diffuse large B-cell lymphoma is limited. The aim of the current study was to comprehensively explore TP53 gene variability resulting from somatic mutations, promoter methylation, and allelic imbalance in tumo...

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Main Authors: Elena N. Voropaeva (Author), Tatyana I. Pospelova (Author), Mikhail I. Voevoda (Author), Vladimir N. Maksimov (Author), Yuriy L. Orlov (Author), Olga B. Seregina (Author)
Format: Book
Published: BMC, 2019-03-01T00:00:00Z.
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