Synthesis, DFT Study, and In Vitro Evaluation of Antioxidant Properties and Cytotoxic and Cytoprotective Effects of New Hydrazones on SH-SY5Y Neuroblastoma Cell Lines

• Hoofdauteurs: Diana Tzankova (Auteur), Hristina Kuteva (Auteur), Emilio Mateev (Auteur), Denitsa Stefanova (Auteur), Alime Dzhemadan (Auteur), Yordan Yordanov (Auteur), Alexandrina Mateeva (Auteur), Virginia Tzankova (Auteur), Magdalena Kondeva-Burdina (Auteur), Alexander Zlatkov (Auteur), Maya Georgieva (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

A series of ten new hydrazide-hydrazone derivatives bearing a pyrrole ring were synthesized and structurally elucidated through appropriate spectral characteristics. The target hydrazones were assessed for radical scavenging activity through 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-b...