Synthesis, DFT Study, and In Vitro Evaluation of Antioxidant Properties and Cytotoxic and Cytoprotective Effects of New Hydrazones on SH-SY5Y Neuroblastoma Cell Lines

• Main Authors: Diana Tzankova (Author), Hristina Kuteva (Author), Emilio Mateev (Author), Denitsa Stefanova (Author), Alime Dzhemadan (Author), Yordan Yordanov (Author), Alexandrina Mateeva (Author), Virginia Tzankova (Author), Magdalena Kondeva-Burdina (Author), Alexander Zlatkov (Author), Maya Georgieva (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of ten new hydrazide-hydrazone derivatives bearing a pyrrole ring were synthesized and structurally elucidated through appropriate spectral characteristics. The target hydrazones were assessed for radical scavenging activity through 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-b...