Block of Voltage-Gated Sodium Channels as a Potential Novel Anti-cancer Mechanism of TIC10

• Главные авторы: Eva Fuchs (Автор), David Alexander Christian Messerer (Автор), Georg Karpel-Massler (Автор), Michael Fauler (Автор), Thomas Zimmer (Автор), Bettina Jungwirth (Автор), Karl Josef Föhr (Автор)
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• Опубликовано: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Предметы: article
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Background: Tumor therapeutics are aimed to affect tumor cells selectively while sparing healthy ones. For this purpose, a huge variety of different drugs are in use. Recently, also blockers of voltage-gated sodium channels (VGSCs) have been recognized to possess potentially beneficial effects in tu...