Block of Voltage-Gated Sodium Channels as a Potential Novel Anti-cancer Mechanism of TIC10

• Päätekijät: Eva Fuchs (Tekijä), David Alexander Christian Messerer (Tekijä), Georg Karpel-Massler (Tekijä), Michael Fauler (Tekijä), Thomas Zimmer (Tekijä), Bettina Jungwirth (Tekijä), Karl Josef Föhr (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background: Tumor therapeutics are aimed to affect tumor cells selectively while sparing healthy ones. For this purpose, a huge variety of different drugs are in use. Recently, also blockers of voltage-gated sodium channels (VGSCs) have been recognized to possess potentially beneficial effects in tu...