Discovery of SIPI6473, a New, Potent, and Orally Bioavailable Multikinase Inhibitor for the Treatment of Non-small Cell Lung Cancer

Abstract A novel series of quinazoline derivatives were designed, synthesized, and evaluated as multikinase inhibitors. Most of these compounds showed antiproliferation activities of several human cancer cell lines and exhibited inhibition efficacy against the estimated glomerular filtration rate (E...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiu Gu (Author), Zi-Xue Zhang (Author), Min-Ru Jiao (Author), Xin-Yan Peng (Author), Jian-Qi Li (Author), Qing-Wei Zhang (Author)
Format: Book
Published: Georg Thieme Verlag KG, 2021-03-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available