Discovery of SIPI6473, a New, Potent, and Orally Bioavailable Multikinase Inhibitor for the Treatment of Non-small Cell Lung Cancer
Abstract A novel series of quinazoline derivatives were designed, synthesized, and evaluated as multikinase inhibitors. Most of these compounds showed antiproliferation activities of several human cancer cell lines and exhibited inhibition efficacy against the estimated glomerular filtration rate (E...
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Format: | Book |
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Georg Thieme Verlag KG,
2021-03-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |