Synthesis and docking study on thiadiazolo[3,2-a][1,3]diazepin-8(5H)-one derivatives as selective GABA(A) agonists

• Główni autorzy: Mohammad javad Taghizadeh (Autor), Abdollah Javidan (Autor), Ali Salmani (Autor)
• Format: Książka
• Wydane: Islamic Azad University, 2016-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

HIE-124 is a new member of ultra-short acting hypnotics' drug family. In this research, the synthesis of analogues of HIE-124 drug in the heterocyclic thiazole ring replaced to thiadiazole, will be presented. Thiadiazolodiazepines during a two-step reaction starting from the amino thiadiazole r...