Synthesis and docking study on thiadiazolo[3,2-a][1,3]diazepin-8(5H)-one derivatives as selective GABA(A) agonists

• Auteurs principaux: Mohammad javad Taghizadeh (Auteur), Abdollah Javidan (Auteur), Ali Salmani (Auteur)
• Format: Livre
• Publié: Islamic Azad University, 2016-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

HIE-124 is a new member of ultra-short acting hypnotics' drug family. In this research, the synthesis of analogues of HIE-124 drug in the heterocyclic thiazole ring replaced to thiadiazole, will be presented. Thiadiazolodiazepines during a two-step reaction starting from the amino thiadiazole r...