Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes

• প্রধান লেখক: Gina M. Coudriet (লেখক), Meghan M. Delmastro-Greenwood (লেখক), Dana M. Previte (লেখক), Meghan L. Marré (লেখক), Erin C. O'Connor (লেখক), Elizabeth A. Novak (লেখক), Garret Vincent (লেখক), Kevin P. Mollen (লেখক), Sojin Lee (লেখক), H. Henry Dong (লেখক), Jon D. Piganelli (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2017-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Oxidative stress and persistent inflammation are exaggerated through chronic over-nutrition and a sedentary lifestyle, resulting in insulin resistance. In type 2 diabetes (T2D), impaired insulin signaling leads to hyperglycemia and long-term complications, including metabolic liver dysfunction, resu...