3-Methyladenine prevents energy stress-induced necrotic death of melanoma cells through autophagy-independent mechanisms
We investigated the effect of 3-methyladenine (3MA), a class III phosphatidylinositol 3-kinase (PI3K)-blocking autophagy inhibitor, on cancer cell death induced by simultaneous inhibition of glycolysis by 2-deoxyglucose (2DG) and mitochondrial respiration by rotenone. 2DG/rotenone reduced ATP levels...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
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Elsevier,
2021-09-01T00:00:00Z.
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