Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage

• المؤلفون الرئيسيون: Joyce E. Gutiérrez (مؤلف), Esteban Fernandez-Moreira (مؤلف), Miguel A. Rodríguez (مؤلف), Michael R. Mijares (مؤلف), Juan Bautista De Sanctis (مؤلف), Soňa Gurská (مؤلف), Petr Džubák (مؤلف), Marián Hajdůch (مؤلف), Julia Bruno-Colmenarez (مؤلف), Luis Rojas (مؤلف), Denis Deffieux (مؤلف), Laurent Pouységu (مؤلف), Stéphane Quideau (مؤلف), Jaime Charris (مؤلف), Hegira Ramírez (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-10-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

A series of 78 synthetic 7-chloro-(4-thioalkylquinoline) derivatives were investigated for cytotoxic activity against eight human cancer as well as 4 non-tumor cell lines. The results showed, with some exceptions, that sulfanyl <b>5</b>-<b>40</b> and sulfinyl <b>41</...