Alzheimer's Disease Enhanced Tonic Inhibition is Correlated With Upregulated Astrocyte GABA Transporter-3/4 in a Knock-In APP Mouse Model

• 主要な著者: Yousif Aldabbagh (著者), Anam Islam (著者), Weicong Zhang (著者), Paul Whiting (著者), Afia B. Ali (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Cognitive decline is a major symptom in Alzheimer's disease (AD), which is strongly associated with synaptic excitatory-inhibitory imbalance. Here, we investigated whether astrocyte-specific GABA transporter 3/4 (GAT3/4) is altered in APP knock-in mouse model of AD and whether this is correlate...