Defining Exposure Predictors of Meropenem That Are Associated with Improved Survival for Severe Bacterial Infection: A Preclinical PK/PD Study in Sepsis Rat Model
<b>Background</b>: The pharmacokinetic/pharmacodynamic (PK/PD) index of carbapenems that best correlates with in vivo antimicrobial activity is percent time of dosing interval in which free drug concentration remains above MIC (%<i>f</i>T > MIC), while the magnitudes of th...
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| Main Authors: | , , , , |
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| Format: | Book |
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MDPI AG,
2022-11-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |