Deciphering the decisive factors driving fate bifurcations in somatic cell reprogramming

• Κύριοι συγγραφείς: Chunshen Long (Συγγραφέας), Hanshuang Li (Συγγραφέας), Pengfei Liang (Συγγραφέας), Lemuge Chao (Συγγραφέας), Yan Hong (Συγγραφέας), Junping Zhang (Συγγραφέας), Qilemuge Xi (Συγγραφέας), Yongchun Zuo (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2023-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Single-cell studies have demonstrated that somatic cell reprogramming is a continuous process of cell fates transition. Only partial reprogramming intermediates can overcome the molecular bottlenecks to acquire pluripotency. To decipher the underlying decisive factors driving cell fate, we identifie...