MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents

• Hoofdauteurs: Tianji Chen (Auteur), Miranda R. Sun (Auteur), Qiyuan Zhou (Auteur), Alyssa M. Guzman (Auteur), Ramaswamy Ramchandran (Auteur), Jiwang Chen (Auteur), Dustin R. Fraidenburg (Auteur), Balaji Ganesh (Auteur), Mark Maienschein-Cline (Auteur), Karl Obrietan (Auteur), J. Usha Raj (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2022-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

MicroRNAs (miRNA, miR-) play important roles in disease development. In this study, we identified an anti-proliferative miRNA, miR-212-5p, that is induced in pulmonary artery smooth muscle cells (PASMCs) and lungs of pulmonary hypertension (PH) patients and rodents with experimental PH. We found tha...