MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents

• Asıl Yazarlar: Tianji Chen (Yazar), Miranda R. Sun (Yazar), Qiyuan Zhou (Yazar), Alyssa M. Guzman (Yazar), Ramaswamy Ramchandran (Yazar), Jiwang Chen (Yazar), Dustin R. Fraidenburg (Yazar), Balaji Ganesh (Yazar), Mark Maienschein-Cline (Yazar), Karl Obrietan (Yazar), J. Usha Raj (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2022-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

MicroRNAs (miRNA, miR-) play important roles in disease development. In this study, we identified an anti-proliferative miRNA, miR-212-5p, that is induced in pulmonary artery smooth muscle cells (PASMCs) and lungs of pulmonary hypertension (PH) patients and rodents with experimental PH. We found tha...