MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents

• প্রধান লেখক: Tianji Chen (লেখক), Miranda R. Sun (লেখক), Qiyuan Zhou (লেখক), Alyssa M. Guzman (লেখক), Ramaswamy Ramchandran (লেখক), Jiwang Chen (লেখক), Dustin R. Fraidenburg (লেখক), Balaji Ganesh (লেখক), Mark Maienschein-Cline (লেখক), Karl Obrietan (লেখক), J. Usha Raj (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2022-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

MicroRNAs (miRNA, miR-) play important roles in disease development. In this study, we identified an anti-proliferative miRNA, miR-212-5p, that is induced in pulmonary artery smooth muscle cells (PASMCs) and lungs of pulmonary hypertension (PH) patients and rodents with experimental PH. We found tha...