MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents

• Váldodahkkit: Tianji Chen (Dahkki), Miranda R. Sun (Dahkki), Qiyuan Zhou (Dahkki), Alyssa M. Guzman (Dahkki), Ramaswamy Ramchandran (Dahkki), Jiwang Chen (Dahkki), Dustin R. Fraidenburg (Dahkki), Balaji Ganesh (Dahkki), Mark Maienschein-Cline (Dahkki), Karl Obrietan (Dahkki), J. Usha Raj (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2022-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

MicroRNAs (miRNA, miR-) play important roles in disease development. In this study, we identified an anti-proliferative miRNA, miR-212-5p, that is induced in pulmonary artery smooth muscle cells (PASMCs) and lungs of pulmonary hypertension (PH) patients and rodents with experimental PH. We found tha...