A systematic efficacy analysis of tuberculosis treatment with BPaL‐containing regimens using a multiscale modeling approach

• Principais autores: Maral Budak (Autor), Laura E. Via (Autor), Danielle M. Weiner (Autor), Clifton E. Barry III (Autor), Pariksheet Nanda (Autor), Gabrielle Michael (Autor), Khisimuzi Mdluli (Autor), Denise Kirschner (Autor)
• Formato: Livro
• Publicado em: Wiley, 2024-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Tuberculosis (TB) is a life‐threatening infectious disease. The standard treatment is up to 90% effective; however, it requires the administration of four antibiotics (isoniazid, rifampicin, pyrazinamide, and ethambutol [HRZE]) over long time periods. This harsh treatment process causes adh...