A systematic efficacy analysis of tuberculosis treatment with BPaL‐containing regimens using a multiscale modeling approach

• Päätekijät: Maral Budak (Tekijä), Laura E. Via (Tekijä), Danielle M. Weiner (Tekijä), Clifton E. Barry III (Tekijä), Pariksheet Nanda (Tekijä), Gabrielle Michael (Tekijä), Khisimuzi Mdluli (Tekijä), Denise Kirschner (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2024-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Tuberculosis (TB) is a life‐threatening infectious disease. The standard treatment is up to 90% effective; however, it requires the administration of four antibiotics (isoniazid, rifampicin, pyrazinamide, and ethambutol [HRZE]) over long time periods. This harsh treatment process causes adh...