The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of <i>Plasmodium falciparum</i> Viability after Antimalarial Treatment In Vitro

• Main Authors: Annabelle Walz (Author), Maëlle Duffey (Author), Ghaith Aljayyoussi (Author), Sibylle Sax (Author), Didier Leroy (Author), Dominique Besson (Author), Jeremy N. Burrows (Author), Mohammed H. Cherkaoui-Rbati (Author), Nathalie Gobeau (Author), Marie-Anne Westwood (Author), Christoph Siethoff (Author), Francisco-Javier Gamo (Author), Pascal Mäser (Author), Sergio Wittlin (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

With artemisinin-resistant <i>Plasmodium falciparum</i> parasites emerging in Africa, the need for new antimalarial chemotypes is persistently high. The ideal pharmacodynamic parameters of a candidate drug are a rapid onset of action and a fast rate of parasite killing or clearance. To d...