The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of <i>Plasmodium falciparum</i> Viability after Antimalarial Treatment In Vitro

• Prif Awduron: Annabelle Walz (Awdur), Maëlle Duffey (Awdur), Ghaith Aljayyoussi (Awdur), Sibylle Sax (Awdur), Didier Leroy (Awdur), Dominique Besson (Awdur), Jeremy N. Burrows (Awdur), Mohammed H. Cherkaoui-Rbati (Awdur), Nathalie Gobeau (Awdur), Marie-Anne Westwood (Awdur), Christoph Siethoff (Awdur), Francisco-Javier Gamo (Awdur), Pascal Mäser (Awdur), Sergio Wittlin (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2023-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

With artemisinin-resistant <i>Plasmodium falciparum</i> parasites emerging in Africa, the need for new antimalarial chemotypes is persistently high. The ideal pharmacodynamic parameters of a candidate drug are a rapid onset of action and a fast rate of parasite killing or clearance. To d...