Interference of DNAJB6/MRJ Isoform Switch by Morpholino Inhibits Replication of HIV-1 and RSV

• Үндсэн зохиолчид: Shih-Han Ko (Зохиогч), Yi-Jen Liau (Зохиогч), Ya-Hui Chi (Зохиогч), Mei-Ju Lai (Зохиогч), Yu-Ping Chiang (Зохиогч), Chun-Yi Lu (Зохиогч), Luan-Yin Chang (Зохиогч), Woan-Yuh Tarn (Зохиогч), Li-Min Huang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2019-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The molecular chaperon MRJ (DNAJB6) exhibits two splice isoforms that have different roles in human viral infection, but the regulatory mechanism of MRJ isoform expression is yet unclear. In this study, we show that reduction of the polyadenylation factor CstF64 was correlated with the increase of t...