Dual Carbonic Anhydrase IX/XII Inhibitors and Carbon Monoxide Releasing Molecules Modulate LPS-Mediated Inflammation in Mouse Macrophages

• প্রধান লেখক: Emanuela Berrino (লেখক), Simone Carradori (লেখক), Andrea Angeli (লেখক), Fabrizio Carta (লেখক), Claudiu T. Supuran (লেখক), Paolo Guglielmi (লেখক), Cecilia Coletti (লেখক), Roberto Paciotti (লেখক), Helmut Schweikl (লেখক), Francesca Maestrelli (লেখক), Elisabetta Cerbai (লেখক), Marialucia Gallorini (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2021-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Low concentrations of carbon monoxide (CO) were reported to exhibit anti-inflammatory effects when administered in cells by suitable chemotypes such as CO releasing molecules (CO-RMs). In addition, the pH-modulating abilities of specific carbonic anhydrase isoforms played a crucial role in different...