New NADPH Oxidase 2 Inhibitors Display Potent Activity against Oxidative Stress by Targeting p22<sup>phox</sup>-p47<sup>phox</sup> Interactions
NADPH oxidase (NOX2) is responsible for reactive oxygen species (ROS) production in neutrophils and has been recognized as a key mediator in inflammatory and cardiovascular pathologies. Nevertheless, there is a lack of specific NOX2 pharmacological inhibitors. In medicinal chemistry, heterocyclic co...
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MDPI AG,
2023-07-01T00:00:00Z.
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